Salt / ingredient
Hydrochlorothiazide 12.5mg + Metoprolol Succinate 50mg
Removes extra fluid, lowers BP + For blood pressure and heart conditions
MRP data last verified: August 2026. Source: NPPA Pharma Sahi Daam, reproduced under the NPPA copyright policy.
Private-brand substitutes: kam se zyada
More about this medicine
Reference information
About Hydrochlorothiazide
This information is from US FDA labels, for reference only. Always follow your doctor's advice.
Common side effects
- headache
- nausea
- diarrhea
- vomiting
- dizziness
- fatigue
- abdominal pain
- constipation
- rash
- insomnia
- tiredness
- depression
- shortness of breath
- bradycardia
- hypotension
- pruritus
Safety advice
- Consult your doctor before use if pregnant or breastfeeding.
- May affect the liver. Tell your doctor if you have liver problems.
- May affect the kidneys. Tell your doctor if you have kidney problems.
- Stop use and seek emergency help if you have signs of a severe allergic reaction.
- May cause low blood sugar. Watch for symptoms like shakiness, sweating, confusion.
Uses
- Lisinopril and hydrochlorothiazide tablets are indicated for the treatment of hypertension, to lower blood pressure.
- Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions.
- These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including lisinopril and hydrochlorothiazide.
- Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake.
- Many patients will require more than 1 drug to achieve blood pressure goals.
How to take
- Lisinopril monotherapy is an effective treatment of hypertension in once-daily doses of 10 mg to 80 mg, while hydrochlorothiazide monotherapy is effective in doses of 12.5 mg to 50 mg per day.
- In clinical trials of lisinopril/hydrochlorothiazide combination therapy using lisinopril doses of 10 mg to 80 mg and hydrochlorothiazide doses of 6.25 mg to 50 mg, the antihypertensive response rates generally increased with increasing dose of either component.
- The side effects (see ) of lisinopril are generally rare and apparently independent of dose; those of hydrochlorothiazide are a mixture of dose-dependent phenomena (primarily hypokalemia) and dose-independent phenomena (e.g., pancreatitis), the former much more common than the latter.
- Therapy with any combination of lisinopril and hydrochlorothiazide will be associated with both sets of dose-independent side effects, but addition of lisinopril in clinical trials blunted the hypokalemia normally seen with diuretics.
- To minimize dose-independent side effects, it is usually appropriate to begin combination therapy only after a patient has failed to achieve the desired effect with monotherapy.
Frequently Asked Questions about Hydrochlorothiazide 12.5mg + Metoprolol Succinate 50mg
What is the price of Hydrochlorothiazide 12.5mg + Metoprolol Succinate 50mg in India?
The price of Hydrochlorothiazide 12.5mg + Metoprolol Succinate 50mg in India depends on the manufacturer and channel.Private commercial brands vary from low-cost options to higher-priced branded formulations.
Is a Government Jan Aushadhi generic available for Hydrochlorothiazide 12.5mg + Metoprolol Succinate 50mg?
Jan Aushadhi generic availability varies. Use the Nearby Kendra locator on Sasta Parcha to find nearby government stores.
How to find lower-cost substitutes for Hydrochlorothiazide 12.5mg + Metoprolol Succinate 50mg?
Search the active salt formulation (Hydrochlorothiazide 12.5mg + Metoprolol Succinate 50mg) on Sasta Parcha to view private-brand substitutes ranked strictly low-to-high by per-unit price. Always consult your prescribing doctor or pharmacist before changing medicine brands.